Don't Minimize, crack, crush, chew, or make an effort to dissolve OxyContin as this tends to impair the controlled-launch shipping system and should lead to a potentially lethal dose of oxycodone. OxyContin may bring about sedation which may impair your reaction competencies and have an affect on your ability to push or run equipment.
Following stopping a CYP3A4 inducer, as the results of the inducer decrease, the oxycodone plasma focus will boost [see Medical PHARMACOLOGY], which could raise or lengthen both the therapeutic results and adverse reactions and could bring about serious respiratory despair.
Tell patients of the potential risk of daily life-threatening respiratory melancholy, including facts that the chance is best when starting OXYCONTIN or once the dosage is improved, and that it might take place even at recommended dosages.
Does oxycodone oral communicate with other medicine that you are getting? Enter your medication to the WebMD conversation checker
Like all entire opioid agonists, there isn't any ceiling result to analgesia for oxycodone. Clinically, dosage is titrated to offer satisfactory analgesia and will be confined by adverse reactions, which includes respiratory and CNS despair.
Approved for use in Grownups and pediatric sufferers aged 11 a get more info long time and more mature who definitely have currently tolerated immediate-release oxycodone but have to have all over-the-clock soreness reduction.
As a consequence of identical pharmacological Houses, it is realistic to be expecting very similar possibility Using the concomitant usage of other CNS depressant prescription drugs with opioid analgesics [see DRUG INTERACTIONS].
Oxycodone is definitely an opioid medication utilized to deal with reasonable to significant pain when other ache treatments usually do not get the job done well adequate. Oxycodone will help lessen suffering by activating opioid receptors during the anxious procedure, as it's an opioid agonist.
To scale back the risk of dizziness and lightheadedness, stand up slowly but website surely when soaring from the sitting down or lying situation.
Opioids cross the placenta and may deliver respiratory melancholy and psycho-physiologic results in neonates. An opioid antagonist, such as naloxone, have to be obtainable for reversal of opioid-induced respiratory despair from the neonate. OXYCONTIN just isn't proposed for use in Ladies promptly prior to labor, when utilization of shorter-acting analgesics or other analgesic tactics tend to be more suitable.
The tablet strengths explain the quantity of oxycodone for every tablet given that the hydrochloride salt. The structural formula for oxycodone hydrochloride is as follows:
Accidental ingestion of even one dose, specifically in children, may result in a fatal overdose of oxycodone.
Further knowledge, such as epidemiological info, when obtainable, might deliver more information on the impact of the current formulation of OXYCONTIN about the abuse legal responsibility of your drug. Appropriately, this portion may very well be up-to-date in the future as proper.
Contact nearby state Skilled licensing board or state-managed substances authority for information check here on how to prevent and detect abuse or diversion of the item.